Prashant Kumar Modi, Ph.D.

Senior Scientific Officer


Dr. Prashant Kumar Modi obtained his Ph.D. from Banaras Hindu University. During this period he studied the effects of aging on glial cells with special emphasis on the astrocytes of the mice brain. During his post-doctoral training at Dr. Pushkar Sharma's laboratory, National Institute of Immunology, New Delhi, he worked on delineating the molecular mechanisms involved in cell cycle related neuronal apoptosis in Alzheimer’s disease. He has been a recipient of DBT Research Associateship during 2011-2015 from Department of Biotechnology, Govt. of India. Currently, he is involved in the identification of biomarkers and novel therapeutic targets in neurodegenerative diseases such as Parkinson’s disease and Alzheimer’s disease using cutting-edge technologies in genomics, proteomics and metabolomics.

Scientific discipline
  • Genomics, proteomics and bioinformatics
  • Neurodegenerative diseases
  • Education
  • Ph.D. in Biochemistry, Banaras Hindu University, India, 2009
  • M.Sc. in Biochemistry, Devi Ahilya University, India, 2002
  • Positions held
    • Faculty Scientist, YU-IOB Center for Systems Biology and Molecular Medicine, Mangalore, India
    • DBT Research Associate, National Institute of Immunology New Delhi, India, 2011-2015
    • Project Associate, National Institute of Immunology New Delhi, India, 2010-2011
    Honors and Awards
    • Awarded SNCI-AIIMS 2013 award for the best oral presentation in 27th Annual Meeting of Society for Neurochemistry, India (SNCI) &International Conference on recent advances in molecular mechanisms in neurological disorders, AIIMS New Delhi
    • DBT Research Associateship( 2011-2012), Dept. of Biotechnology, India, 2011-2012
    • Senior Research Fellowship(2007-2009), Indian Council of Medical Research, India, 2007-2009
    • Qualified CSIR-UGC NET(LS) December, 2002

    Research papers:6; Review articles: 0; Book Chapters: 0

    • Modi, P. K., Prabhu, A., Bhandary, Y. P., Shenoy, P. S., Hegde, A., Es, S. P., Johnson, R. P., Das, S. P., Vazirally, S., Rekha, P. D. (2019). Effect of calcium glucoheptonate on proliferation and osteogenesis of osteoblast-like cells in vitro. PLos One. 14, e0222240. [PubMed]
    • Deolankar, S. C., Patil, A. H., Koyangana, S. G., Subbannayya, Y., Prasad, T. S. K. and Modi, P. K*. (2019). Dissecting Alzheimer’s disease molecular substrates by proteomics and discovery of novel post-translational modifications (PTMs). OMICS: A Journal of Integrative Biology. In Press. (* corresponding author)
    • Sahu, A., Gopalakrishnan, L., Gaur, N., Chatterjee, O., Mol, P., Modi, P. K., Dagamajalu, S., Advani, J., Jain, S. and Prasad, T. S. K. (2018). The 5-Hydroxytryptamine signaling map: an overview of the serotonin-serotonin receptor-mediated signaling network. Journal of Cell Communication and Signaling. 12, 731-735. [PubMed]
    • Modi, P. K., Jaiswal, S. and Sharma P. (2016). Regulation of Neuronal Cell Cycle and Apoptosis by MicroRNA 34a. Molecular and Cellular Biology. 36:84-94. [PubMed]
    • Modi, P. K.*, Komaravelli, N.*, Singh, N. and Sharma P. (2012). Interplay between MEK-ERK signaling, cyclin D1 and cyclin dependent kinase 5 regulates cell cycle reentry and apoptosis of neurons. Molecular Biology of the Cell. 18:3722-30. (Recommended by the faculty of 1000), (*Equal contribution). [PubMed]
    • Modi, P. K. and Kanungo, M. S. (2010). Age-dependent expression of S100beta in the brain of mice. Cellular and Molecular Neurobiology. 5:709-16. [PubMed]