Keshava K. Datta, Ph.D.



Dr. Keshava K. Datta pursued his Ph.D. from Institute of Bioinformatics, Bangalore and KIIT University, Bhubaneswar. During his Ph.D., he carried out proteomic and proteogenomic analysis of an opportunistic pathogen - Candida tropicalis. Prior to Ph.D., he worked as a faculty at the CMR Institute of Management and Science in Bangalore where he taught membrane biochemistry, molecular physiology and fundamentals of biochemistry. Currently, He is involved in the analysis of proteomic data and also teaching concepts of proteomics, proteogenomics and OMICS data analysis to postgraduate and diploma students.

Scientific discipline
  • Cancer Biology
  • Biomarkers for non-infectious diseases
  • Proteomics and proteogenomics
  • Education
  • Ph.D. in Biotechnology, Institute of Bioinformatics, KIIT University, India, 2017
  • M.Sc. in Biochemistry, Bangalore University, India, 2008
  • Positions held
    • Faculty, Department of Bioscience, CMR Institute of Management and Science (Autonomous), Bangalore
    Honors and Awards
    • Cleared CSIR-UGC- JRF-NET with all India ranking 65 in July 2011

    Research papers: ; Review articles: ; Book Chapters:

    • Tiwari, R., Sahu, I., Soni, B. L., Sathe, G. J., Datta, K. K., Thapa, P., Sinha, S., Vadivel, C. K., Dhaka, B., Sinha, S., Gowda, H. and Vaidya, M. M. (2017). Quantitative phosphoproteomic analysis reveals system-wide signaling pathways regulated by site-specific phosphorylation on Keratin-8 in skin squamous cell carcinoma derived cell-line. Proteomics. [Pubmed]
    • Raja, R., Sahasrabuddhe, N. A., Radhakrishnan, A., Syed, N., Solanki, H. S., Puttamallesh V. N., Balaji, S. A., Nanjappa V., Datta, K. K., Babu, N., Renuse, S., Patil, A. H., Izumchenko, E., Prasad, T. S., Chang X., Rangarajan A., Sidransky, D., Pandey, A., Gowda, H., Chatterjee, A. (2016). Chronic exposure to cigarette smoke leads to activation of p21 (RAC1)-activated kinase 6 (PAK6) in non-small cell lung cancer cells. Oncotarget. 7, 61229-45. [PubMed]
    • Datta, K. K., Patil, A. H., Patel, K., Dey, G., Madugundu, A. K., Renuse, S., Kaviyil, J. E., Nirujogi, R. S., Arunima, A., Daswani, B., Kaur, I., Mohanty, J., Sinha, R., Jaiswal, S., Sivapriya, S., Sonnathi, Y., Chattoo, B. B., Gowda, H., Ravikumar, R. and Prasad, T. S. K. (2016). Proteogenomics of Candida tropicalis - an opportunistic pathogen with importance for global health. OMICS: A Journal of Integrative Biology. 20, 239-47. [PubMed]
    • Datta, K. K., Madugundu, A. K. and Gowda, H. (2016). Proteogenomic Methods to Improve Genome Annotation. Methods in Molecular Biology. 1410, 77-89. [PubMed]
    • Datta, K. K., Dhaka, B., Patel, K., Puttamallesh, V. and Gowda, H. (2016). Phosphoproteomic profiling using biopsy-scale protein amounts. Journal of Proteins and Proteomics. 7, 305-309. [PubMed]
    • Prasad, T. S. K., Mohanty, A. K., Kumar, M., Sreenivasamurthy, S. K., Dey, G., Nirujogi, R. S., Pinto, S. M., Madugundu, A. K., Patil, A. H., Advani, J., Manda, S. S., Gupta, M. K., Dwivedi, S. B., Kelkar, D. S., Hall, B., Jiang, X., Peery, A., Rajagopalan, P., Yelamanchi, S. D., Solanki, H. S., Raja, R., Sathe, G. J., Chavan, S. N., Verma, R., Patel, K. M., Jain, A. P., Syed, N., Datta, K. K., Khan, A. A., Dammalli, M., Jayaram, S., Radhakrishnan, A., Mitchell, C. J., Na, C. H., Kumar, N., Sinnis, P., Sharakhov, I. V., Wang, C., Gowda, H., Tu, Z., Kumar, A., and Pandey, A. (2016). Integrating transcriptomic and proteomic data for accurate assembly and annotation of genomes. Genome Research. 27, 133-144. [PubMed]
    • Sharma, J., Balakrishnan, L., Datta, K. K., Sahasrabuddhe, N. A., Khan A. A., Sahu, A., Singhal, A., Derese, G., Raju, R., Chatterjee, A., Gowda, H., Prasad, T. S. K., Shankar, S. and Pandey, A. (2015). A knowledgebase resource for Interleukin-17 family mediated signaling. Journal of Cell Communication and Signaling. 9, 291-296. [PubMed]
    • Mir, S. A., Rajagopalan, P., Jain, A. P., Khan, A. A., Datta, K. K., Mohan, S. V., Lateef, S. S., Sahasrabuddhe, N., Somani, B. L., Prasad, T. S. K., Chatterjee, A., Kumar, K. V. V., Kumar, M. V., Kumar, R. V., Gundimeda, S., Pandey, A. and Gowda H. (2015). LC-MS-based serum metabolomic analysis reveals dysregulation of phosphatidylcholines in esophageal squamous cell carcinoma. Journal of Proteomics. S1874-3919. [PubMed]
    • Syed, N., Barbhuiya, M. A., Pinto, S. M., Nirujogi, R. S., Renuse, S., Datta, K. K., Khan, A. A., Srikumar, K., Prasad, T. S. K., Vijaya Kumar, M., Kumar, R. V., Chatterjee, A., Pandey, A. and Gowda, H. (2015). Phosphotyrosine profiling identifies ephrin receptor A2 as a potential therapeutic target in esophageal squamous cell carcinoma. Proteomics. 15, 374-382. [PubMed]
    • Sharma, A., Varghese, A. M., Vijaylakshmi, K., Sumitha, R., Prasanna, V. K., Shruthi, S., Sagar, C. B. K., Datta, K. K., Gowda, H., Nalini, A., Alladi, P. A., Christopher, R., Sathyaprabha, T. N., Raju, T. R and Bharath, S. M. M. (2015). Cerebrospinal Fluid from Sporadic Amyotrophic Lateral Sclerosis Patients Induces Mitochondrial and Lysosomal Dysfunction. Neurochemical Research. 41, 965-84. [PubMed]
    • Manda, S. S., Nirujogi, R. S., Pinto, S., Kim, M. S., Datta, K. K., Sirdeshmukh, R., Prasad, T. S. K., Thongboonkerd, V., Pandey, A. and Gowda, H. (2014). Identification and characterization of proteins encoded by chromosome 12 as part of Chromosome-centric Human Proteome Project. Journal of Proteome Research. 13, 3166-3177. [PubMed]
    • Kelkar, D. S., Provost. E., Chaerkady, R., Muthusamy, B., Manda, S. S., Subbannayya, T., Selvan, L. D. N., Wang, C. H., Datta, K. K., Woo, S., Dwivedi, S. B., Renuse, S., Getnet, D., Huang, T. C., Kim, M. S., Pinto, S. M., Mitchell, C. J., Madugundu, A. K., Kumar, P., Sharma, J. Advani, J., Dey, G., Balakrishnan, L., Syed, N., Nanjappa, V., Subbannayya, Y., Goel, R., Prasad, T. S. K., Bafna, V., Sirdeshmukh, R., Gowda, H., Wang, C., Leach, S. D. and Pandey, A. (2014). Annotation of the zebrafish genome through an integrated transcriptomic and proteomic analysis. Molecular and Cellular Proteomics. 13, 3184-98. [PubMed]
    • Kim, M. S., Pinto, S. M., Getnet, D., Nirujogi, R. S., Manda, S. S., Chaerkady, R., Madugundu, A. K., Kelkar, D. S., Isserlin, R., Jain, S., Thomas, J. K., Muthusamy, B., Leal-Rojas, P., Kumar, P., Sahasrabuddhe, N. A., Balakrishnan, L., Advani, J., George, B., Renuse, S., Selvan, L. D. N., Patil, A. H., Nanjappa, V., Radhakrishnan, A., Prasad, S., Subbannayya, T., Raju, R., Kumar, M., Sreenivasamurthy, S. K., Marimuthu, A., Sathe, G. J., Chavan, S., Datta, K. K., Subbannayya, Y., Sahu, A., Yelamanchi, S. D., Jayaram, S., Rajagopalan, P., Sharma, J., Murthy, K. R., Syed, N., Goel, R., Khan, A. A., Ahmad, S., Dey, G., Mudgal, K., Chatterjee, A., Huang, T. C., Zhong, J., Wu, X., Shaw, P. G., Freed, D., Zahari, M. S., Mukherjee, K. K., Shankar, S., Mahadevan, A., Lam, H., Mitchell, C. J., Shankar, S. K., Satishchandra, P., Schroeder, J. T., Sirdeshmukh, R., Maitra, A., Leach, S. D., Drake, C. G., Halushka, M. K., Prasad, T. S. K., Hruban, R. H., Kerr, C. L., Bader, G. D., Iacobuzio-Donahue, C. A., Gowda, H. and Pandey, A. (2014). A draft map of the human proteome. Nature. 509, 575-581. [PubMed]